The Brazilian midfielder lines up alongside Virgil van Dijk at the heart of the Reds’ defence, while Jordan Henderson takes up his place in midfield despite only returning to training on Friday afternoon.
Joel Matip is fit enough for the bench, though.
Henderson will start alongside Gini Wijnaldum in midfield, in a 4-2-3-1 shape.
There’s no Daniel Sturridge in the squad, the striker ruled out due to illness.
Subs: Mignolet, Moreno, Matip, Camacho, Milner, Keita, Origi
Brighton: Button, Montoya, Dunk, Duffy, Bong, Propper, Stephens, Gross, March, Murray, Locadia
Subs: Steele, Balogun, Bruno, Kayal, Sanders, Knockaert, Andone